CHAPTER 1. Cell cycle and apoptosis as they pertain to chemotherapy
Péter Bősze

CHAPTER 2. Mechanisms of action of the cytotoxic drugs in gynecologic oncology
John P. Geisler, Kelly J. Manahan, Georgiann C. Linnemeier, Michael C. Wiemann

CHAPTER 3. Clinical pharmacologic principles of the administration of cytotoxic and cytostatic agents in solid tumor therapy
Sándor Kerpel-Fronius

CHAPTER 4. Drug resistance and tumor heterogeneity
Kelly J. Manahan, John P. Geisler, Georgiann C. Linnemeier, Michael C. Wiemann

CHAPTER 5. Principles and process of cancer drug development: clinical trial methodology in gynecologic cancer
Anastasia Anastasopoulou

CHAPTER 6. Emerging genomic technology in cancer research: its application in discovering and developing new therapeutic agents
János L. Tanyi, Kwai Wa Cheng, John P. Lahad, Gordon B. Mills

CHAPTER 7. Cytotoxic drugs in gynecologic oncology
Claire F. Verschraegen, John Bibb

CHAPTER 8. Safety of cytotoxic drug handling, preparation, storage, etc: the role of the pharmacists and nurses
Piero Sismondi, Annamaria Ferrero, Franca Goffredo, D. Rosella Marchese, Francesco Marocco, Daniela Dompè

CHAPTER 9. Practical implications of cytotoxic drug administration
Jan Van den Brande, Jan B. Vermorken

CHAPTER 10. "Chemosensitivity testing" in the management of patients with gynecologic malignancies
Maurie Markman

CHAPTER 11. Drug toxicity prevention and management
Gavin M. Marx, Michael L. Friedlander

CHAPTER 12. Psychological aspect of chemotherapy
Stefanie Schwartz, Katherine M. Zahasky

CHAPTER 13. Chemotherapy for gynecologic cancer: definitions and methodological aspects
Ignacio Tusquets, Santiago Dexeus

CHAPTER 14. The dosing, schedule and route of chemotherapy in gynecologic cancers
Ahmad Awada, Max Mano, Martine Piccart, Fatima Cardoso, Lissandra Dal Lago

CHAPTER 15. Current status of cytotoxic drug treatment of non-epithelial ovarian tumors
M™Jose Safont, Andres Poveda

CHAPTER 16. Chemotherapy in the management of cervix cancer
Maurie Markman

CHAPTER 17. Chemotherapy in the management of endometrial cancer
Maurie Markman

CHAPTER 18. Cytotoxic drug treatment of vulval and vaginal cancer
Michelle M. Harrison, Gavin M. Marx, Neville F. Hacker, Michael L. Friedlander

CHAPTER 19. Current status of cytotoxic treatment of gestational trophoblastic disease
Colleen M. Feltmate, Donald P. Goldstein, Ross S. Berkowitz

CHAPTER 20. Current status of cytotoxic treatment of breast cancer
Lajos Pusztai, János Tanyi, Gabriel N. Hortobágyi

CHAPTER 21. High-dose chemotherapy in the management of gynecologic malignancies
Maurie Markman

CHAPTER 22. Intraperitoneal chemotherapy in gynaecologic oncology
Maurie Markman

CHAPTER 23. A rational approach to the chemotherapeutic management of ovarian, cervical and endometrial cancers
Maurie Markman

CHAPTER 24. The current status of chemoprevention of breast cancer
Alberto Costa, Davide Serrano, Bettina Ballardini, Andrea Decensi

CHAPTER 25. Targeted molecular cancer therapy: today and tomorrow
Sándor Eckhardt

CHAPTER 26. Future strategies in the prevention and treatment of gynecologic cancers
Claire F Verschraegen